Do you remember this iconic show?

Three cartoon characters stand in a school hallway with lockers behind them. A large boy in a blue shirt stands with a smug expression. A girl with orange hair stands with her arms crossed looking annoyed. A boy in a red shirt with spiky hair holds his head in his hands looking distressed. The text overlaid at the bottom reads 'WADE OUT OF HIS BEDROOM' and 'A SURE SIGN OF THE APOCALYPSE'.